Blog Post
Ossianix publishes a research article
- by kbw
- •
- 25 Jun, 2016
We published a research article in Molecular Immunology. Highlights: VNARs to BAFF with low nM potency were isolated from a semi-synthetic phage library. The CDR3 regions contain a conserved DXL motif found in all three BAFF receptors. VNARs to BAFF block B cell proliferation in response to either human or mouse BAFF. A chimeric VNAR-Fc […]
We published a research article in Molecular Immunology.
Highlights:
- VNARs to BAFF with low nM potency were isolated from a semi-synthetic phage library.
- The CDR3 regions contain a conserved DXL motif found in all three BAFF receptors.
- VNARs to BAFF block B cell proliferation in response to either human or mouse BAFF.
- A chimeric VNAR-Fc fusion protein inhibited splenic B cell development in mice.
To read more access it online here.